Leveraging our cutting-edge technology based on protein dynamics, Nutshell is fostering a new
era of drug discovery…
Our AlloStar allosteric drug discovery platform, composed of a
powerful and well-integrated set of computational modules and experimental tools based on our proprietary
AI algorithm and deep know-how derived from biochemistry and biophysics, possesses the unique capability
to discover a host of drug entities including various types of protein activators, subtype/mutation
selective small molecules, regulatory molecules of protein-protein interaction (PPI) and stabilizer of
intrinsically disordered proteins (IDPs), thus opening up an unprecedented new horizon for small molecule
innovation.


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Sub-type selective allosteric inhibitor
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Mutants selective allosteric inhibitor
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Enzyme allosteric activator
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Protein-protein interaction modulator
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Disordered protein stabilize modulator
Current Pipeline
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Project
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Indication
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MoA
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Discovery
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Hit-to-Lead
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PCC
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Clinical I-III
Contact Us
Building E, No.1976 Middle Gaoke Rd. Pudong district, Shanghai, China
021-51061769
contact@allonutshell.com;BD@allonutshell.com
